Side Effects of Coenzyme Q10:
The use of Coenzyme Q10 has produced
no serious side effects. Some Coenzyme Q10 patients have experienced a
mild inability to sleep, liver enzymes levels have been elevated,
rashes, nausea, and upper abdominal pain. Some reported Coenzyme Q10
side effects include dizziness, irritability, headache, fatigue,
heartburn, and visual sensitivity to light. There should always be some
precautions when other prescription drugs are used in conjunction with
Coenzyme Q10. The possible interaction between Coenzyme Q10 and
prescribed drugs need to be discussed with a health care provider.
Certain drugs, such as those that are used to lower cholesterol or
blood sugar levels, may reduce the effects of Coenzyme Q10. Coenzyme
Q10 may also alter the body’s response to Warfarin (a drug that
prevents the blood from clotting) and insulin. In the study conducted for Parkinson’s
Disease, it was cautioned that Coenzyme Q10 is classified as a dietary
supplement and should not be used until a larger study is conducted
with definitive results. Trials may be difficult in the future without
enough patients to carry out definitive studies of the compound's
effectiveness and proper dosages. Coenzyme Q10 is not yet regulated by
the U.S. Food and Drug Administration. The Coenzyme Q10 supplement
versions that are currently sold in stores may differ from the trial
Coenzyme Q10 compounds. These supplement versions of Coenzyme Q10 may
not contain potentially beneficial amounts of the compound.
Additionally taking Coenzyme Q10 over a number of years may be costly. A daily dosage (50-150mg) of Coenzyme
Q10 study in heart failure showed a low incidence of side effects and
a general interpretation of an improved quality of life index.1
Most side effects of
coenzyme Q10
were mild, and none of the patients required a reduction of their
dose.
The patients have received the largest
dose of coenzyme Q10
(1,200 mg/day) had 44 percent less decline in mental function, motor
(movement) function, and ability to carry out activities of daily
living, such as feeding or dressing themselves. The greatest effect
was on activities of daily living.
1Italian multicenter study of
coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug
Surveillance Investigators. Coenzyme Q10 Withdrawal - Clinical Relapse
in Congestive Heart Failure Patients
MEDLINE EXPRESS (R) 1991-1995
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